Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control ...

Unlike many trendy diets, intermittent fasting appears to deliver real benefits—provided dieters can stick to the schedule, which usually restricts eating to an eight-hour window each day. Dieters, ...

Findings underpin the scientific rationale for Anavex’s targeted autophagy approach with orally administered blarcamesine. Convergence of impaired autophagy and synaptic dysfunc ...

Scientists are working hard to find better ways to treat brain diseases such as Alzheimer’s disease and frontotemporal ...

In a twist that blurs the lines between two devastating diseases, scientists have spotted dementia-like behavior in the pancreas. In mice, pancreatic cells teetering on the brink of cancer began to ...

Researchers at the University Hospital Bonn have identified a breakdown in autophagy, the cell’s recycling system, as the primary cause of myofibrillar myopathy type 6 (MFM6). Using a humanized mouse ...

Most of us think about aging as something that happens to us gradually, almost invisibly, like the slow fading of a ...

While radiation therapy is an effective tool to destroy cancer cells, a new study from Vanderbilt researchers suggests that ...