Scientists are refining electroporation methods to improve CRISPR/Cas9 gene editing efficiency while preserving cell health. By adjusting buffer composition, pulse parameters, and delivery formats, ...

Researchers in Basel have created SEED/Harvest, a new CRISPR-based technique that tags proteins without leaving any genetic “scars.” By blending two powerful methods, it allows scientists to study ...

A CRISPR Therapy Just Cured A Disease From Inside The Body For The First Time. The Gene-Editing Era Officially Started Monday ...

CRISPR-Cas9 is an RNA-guided DNA-cutting enzyme system that allows researchers to modify the genetic code of virtually any organism with a precision, speed, and affordability previously unattainable.

In 2020, Jennifer Doudna, Ph.D., received the Nobel Prize in Chemistry, CRISPR-Cas9, a method for genome editing. Often referred to as “molecular scissors,” CRISPR cuts DNA at specific locations that ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

A new method called Tracking-seq can spot off-target effects across multiple CRISPR genome editing tools in just 1–2 weeks. By tracing replication protein A bound to single-stranded DNA, it reveals ...

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited ...

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals. To better monitor the emergence and spread of resistance, ...

On the left: poplar sprouts containing CRSPR-edited gene. On the right, poplar sprouts with the same CRSPR edit plus gene enhancements to improve growth. Credit: UMD Ten years ago, a new technology ...