A study led by scientists at Duke-NUS Medical School has identified the pivotal but previously unknown role of an enzyme, called FAXDC2, that is suppressed in cancers with hyperactive Wnt signalling.

In this study, the researchers investigated the Aster protein family, which is known to bind cholesterol and help it move from one membrane to another. "How cholesterol that enters the cell through ...

How cholesterol that enters the cell through NPC1L1 reaches the endoplasmic reticulum for esterification and regulation of cholesterol synthesis has been a longstanding mystery. We solve that mystery ...

Scientists led by a team at Duke-NUS Medical School have made a breakthrough in understanding the mechanisms that influence cancer cell growth and development. Publishing in the Journal of Clinical ...

UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream – potentially ...

A study has found an important connection between cancer, stem cells and the building blocks of cholesterol. Specifically, the research reveals how the enzyme FAXDC2 influences cancer cell growth and ...

Scientists at UCLA described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream. The finding might ...