Model for ORF1p-RNP formation and DNA recognition. ORF1p forms homo trimers and higher-order oligomers that can bind to DNA but have a clear preference for RNA. Credit: Sarah Zernia et al Model for ...
Our DNA is constantly being packed and unpacked. And there is a good reason for this: depending on its packing state, it performs different functions in the cell nucleus. For most of its life – this ...
For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
If DNA bridges remain between chromosomes after cell division, chromosome segregation can be disrupted, leading to genetic instability and increasing the risk of cancer. Researchers at UNIST and the ...
DNA does not float freely in the cell. Instead, it is wrapped around histone proteins to form structures called nucleosomes.
Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within ...
New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our understanding of how bacteria manage DNA. The methods enabled researchers to uncover ...
If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...
Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...
New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our ...
(Nanowerk News) If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell ...
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