Phagocytes such as macrophages and neutrophils contain multiple lysosomes, which possess a variety of digestive enzymes. Upon stimulation, phagocytes secrete these digestive enzymes through a process ...

Mononuclear phagocytes can both promote and inhibit inflammation. A team has now shown that individual phagocytes in the central nervous system can play both roles, sequentially adopting different ...

Every day, billions of damaged or unnecessary cells die and are swept away by the immune system’s cleanup crew—phagocytes. But when that clearance falters, dangerous cells can linger, fueling cancer ...

It is known that the immune response in pregnant women undergoes recognized changes that ensure the mother does not reject the fetus. Dysregulation of this dynamic immune adaptation underpins numerous ...

The engulfment ability of a phagocyte is controlled by its mitochondrial membrane potential (MMP), according to a study by Ravichandran and colleagues. The authors reasoned that the 'ingestion' of ...